MOTION SICKNESS PATCH FOR KIDS PATCH

14ĭahl and colleagues conducted a study comparing scopolamine patches to meclizine 25 mg and placebo for prevention of motion sickness. AEs associated with treatment included dry mouth, drowsiness, and blurred vision, and only dry mouth occurred more frequently with scopolamine than with dimenhydrinate. Scopolamine and dimenhydrinate provided greater protection than placebo, but a direct comparison of scopolamine and dimenhydrinate was not completed.

MOTION SICKNESS PATCH FOR KIDS PATCH

The transdermal scopolamine patch was applied 4 to 16 hours before patients sailed on a ship for 7 to 8 hours dimenhydrinate and placebo were administered 1.5 hours before motion exposure and 2.5 hours after motion began. 14 Patients were given a transdermal scopolamine patch, oral dimenhydrinate, or placebo. Price and colleagues compared transdermal scopolamine and dimenhydrinate for prevention of seasickness.

Adverse effects (AEs) in all groups were minimal, with gait disturbances occurring occasionally after application of two scopolamine patches. Dimenhydrinate was more effective than the single scopolamine patch for reducing nausea. Both scopolamine groups and the dimenhydrinate group experienced a greater reduction in nausea compared with the placebo group. The scopolamine patches were applied 6 to 8 hours before motion exposure. 16 Patients received one transdermal scopolamine patch, two transdermal scopolamine patches, oral dimenhydrinate 100 mg, or placebo. In a randomized, double-blind, placebo-controlled study, Pyykkö and colleagues evaluated the use of transdermal scopolamine and oral dimenhydrinate for treatment of motion sickness.

10-13 Concerning the time of application, there was a greater benefit when the patch was applied 8 to 16 hours before motion exposure than when it was applied <4 hours beforehand. 7-9 In sea studies including patients with and without a history of motion sickness, transdermal scopolamine was more efficacious than placebo for preventing motion sickness. Overall, the efficacy of scopolamine was found to be similar to that of dimenhydrinate and greater than that of promethazine. In these trials, scopolamine was demonstrated to be superior to placebo for preventing motion sickness.Ĭomparisons of scopolamine and antihistamines have yielded varying results. In addition, various dosages of scopolamine were compared. 7-9 Multiple studies were conducted to compare the scopolamine transdermal patch with placebo and antihistamines (dimenhydrinate, promethazine). 5,6 Although scopolamine is available in several dosage forms, the most common form used for motion sickness is the transdermal patch.Įarly studies were conducted in healthy volunteers who participated in the Spacelab missions in the 1970s and 1980s. Additionally, it decreases gastrointestinal secretions and motility and inhibits the secretion of saliva and sweat. This agent prevents motion sickness via its anticholinergic effects. Scopolamine is one of the most commonly prescribed medications for the treatment or prevention of motion sickness. Both pharmacologic and nonpharmacologic agents are available. 3,4 Numerous treatment and prevention options for motion sickness exist, as described in TABLE 1. Additionally, motion sickness may be caused by certain medications, including but not limited to macrolides, metronidazole, morphine, digoxin, and some selective serotonin reuptake inhibitors. Patients with a history of migraines may be more likely to experience motion sickness. Women are more likely than men to experience motion sickness, especially during pregnancy or menstruation or in those taking hormone therapy.

Children aged 2 to 12 years are more susceptible to the condition than those aged <2 years. Susceptibility to motion sickness varies among individuals. It can begin suddenly, with signs and symptoms including dizziness, nausea, and vomiting. 1 Motion sickness can manifest during air travel and in cars or trains, but it occurs most frequently during boat travel (seasickness). Motion sickness occurs when the motion perceived visually does not match that sensed by the brain.

The brain normally receives signals from the inner ears, eyes, muscles, and joints. Motion sickness is a common occurrence for many people during travel.

All agents can cause unwanted side effects and have precautions for specific patient populations. Although there are several OTC options for motion sickness, it is important for pharmacists to consider individual patient characteristics before making a recommendation.

Several effective pharmacologic treatments are available, including both prescription and OTC medications. Some people are more susceptible to motion sickness than others. ABSTRACT: Motion sickness is a common malady in the general population however, the exact mechanism through which it occurs is not completely known.

Motion sickness patch for kids